For their research, Kyung-Chul Choi and colleagues from Chungbuk National University and the Korea Research Institute of Bioscience and Biotechnology looked at triclosan in the context of how it affects the hormonal system. A known hormone-disruptor, triclosan has been shown in previous research to mimic the feminizing hormone estrogen, which in turn alters the normal production and expression of other hormones like testosterone.
As a result, triclosan appears to throw the endocrine system out of balance, leading to abnormal cellular growths. Particularly in women, triclosan appears to trigger the growth of breast cancer cells, leading to the formation of malignant tumors. This was demonstrated both in cell samples and in live mice, as breast cancer cells were shown to thrive in the presence of triclosan.
After comparing the frequency and progression patterns of breast cancer growth in both the cell samples and the mice, some of which were exposed to triclosan and some of which were not, it became clear that the chemical spurs abnormal cell proliferation. And the fact that triclosan bioaccumulates in the body over time makes the threat of it even more pronounced.
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